Question:
Complications associated with administration of Clozapine, an antipsychotic drug
Complications associated with administration of Clozapine, an antipsychotic drug
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Clozapine = "Close monitoring" of the WBC count (Agranulocytosis).
Updated On: May 25, 2026
- Extrapyramidal syndrome
- Blood dyscrasia
- Hepatotoxicity
- Hemolytic anaemia
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The Correct Option is B
Solution and Explanation
Step 1: Concept
Clozapine is an atypical (second-generation) antipsychotic used for treatment-resistant schizophrenia.
Step 2: Meaning
Blood dyscrasia refers to a morbid general state resulting from the presence of abnormal material in the blood, specifically agranulocytosis in this context.
Step 3: Analysis
Unlike typical antipsychotics, Clozapine has a very low risk of extrapyramidal side effects. However, it carries a "Black Box" warning for agranulocytosis (a severe drop in white blood cell count).
Step 4: Conclusion
Because of this risk, patients on Clozapine require regular hematological monitoring. Final Answer: (B)
Clozapine is an atypical (second-generation) antipsychotic used for treatment-resistant schizophrenia.
Step 2: Meaning
Blood dyscrasia refers to a morbid general state resulting from the presence of abnormal material in the blood, specifically agranulocytosis in this context.
Step 3: Analysis
Unlike typical antipsychotics, Clozapine has a very low risk of extrapyramidal side effects. However, it carries a "Black Box" warning for agranulocytosis (a severe drop in white blood cell count).
Step 4: Conclusion
Because of this risk, patients on Clozapine require regular hematological monitoring. Final Answer: (B)
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