Question:
Quinidine and procainamide acts by which mechanism of action:
Quinidine and procainamide acts by which mechanism of action:
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Class IA: Open state blockers with intermediate kinetics.
Updated On: May 25, 2026
- Block inactive Sodium ion channel
- Multi channel blocking agent
- Block L- type Ca+ ion channel
- Block sodium ion in open state
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The Correct Option is D
Solution and Explanation
Step 1: Concept
Quinidine and Procainamide are Class IA antiarrhythmic drugs.
Step 2: Meaning
The mechanism of action defines how a drug interacts with cellular components to produce its pharmacological effect.
Step 3: Analysis
Class I antiarrhythmics are primarily sodium channel blockers. Class IA agents specifically have an intermediate rate of association and dissociation with the sodium channels, predominantly binding to them when they are in the open or activated state.
Step 4: Conclusion
This action slows the rate of rise of the action potential (Phase 0) and prolongs the refractory period. Final Answer: (D)
Quinidine and Procainamide are Class IA antiarrhythmic drugs.
Step 2: Meaning
The mechanism of action defines how a drug interacts with cellular components to produce its pharmacological effect.
Step 3: Analysis
Class I antiarrhythmics are primarily sodium channel blockers. Class IA agents specifically have an intermediate rate of association and dissociation with the sodium channels, predominantly binding to them when they are in the open or activated state.
Step 4: Conclusion
This action slows the rate of rise of the action potential (Phase 0) and prolongs the refractory period. Final Answer: (D)
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