Question:

The most active estrogen found naturally in the human body is:

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Remember the order of potency: Estradiol (E2) > Estrone (E1) > Estriol (E3).
Updated On: May 25, 2026
  • Estrone
  • Estradiol
  • Progesterone
  • Estriol
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The Correct Option is B

Solution and Explanation

Step 1: Concept
Estrogens are a group of steroid hormones crucial for the development and maintenance of female reproductive structures.

Step 2: Meaning

Activity refers to the potency or the strength of the biological response elicited by the hormone upon binding to its specific receptors.

Step 3: Analysis

While Estrone (E1), Estradiol (E2), and Estriol (E3) are all natural estrogens, Estradiol is the predominant and most potent form produced during the reproductive years. Progesterone is a progestogen, not an estrogen.

Step 4: Conclusion

Based on receptor binding affinity and physiological impact, Estradiol is recognized as the most active estrogen. Final Answer: (B)
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