List of practice Questions

Which class of antibiotics characteristically shows concentration-dependent killing?
The posterior cricoarytenoid (PCA) muscle of the larynx is the only muscle that performs which action on the vocal cords?
Which of the following carbohydrates is a NON-reducing sugar and therefore gives a NEGATIVE Benedict’s (and Fehling’s) test?
A child develops cola-coloured urine, periorbital oedema and hypertension two weeks after a sore throat. Urine microscopy shows red blood cell casts. On electron microscopy of the renal biopsy, which finding is characteristic of this condition?
Transplacental transfer of maternal anti-Ro (SS-A) and anti-La (SS-B) antibodies is most characteristically associated with which neonatal condition?
A histology slide of myocardium is taken from a patient who died 1-3 days after an acute myocardial infarction. Which of the following cellular changes is MOST characteristic of this time interval?
Hand-eye coordination, integration of visual and somatosensory information, and spatial awareness are mainly functions of which lobe of the cerebral cortex?
The inguinal ligament (Poupart’s ligament), forming the floor of the inguinal canal, is a modification of the lower border of the aponeurosis of which muscle?
An inhaled foreign body more commonly lodges in the right main bronchus than the left. Which set of features of the right main bronchus BEST explains this tendency?
An ECG shows ST-segment elevation in leads II, III and aVF in a patient presenting with acute chest pain. Which coronary artery is most likely occluded?
A patient with long-standing rheumatoid arthritis develops nephrotic-range proteinuria. Renal biopsy with Congo red stain shows apple-green birefringence under polarised light. Which type of amyloid protein is most likely deposited?
The plasma drug-concentration versus time curve shown declines such that the half-life remains constant regardless of the starting concentration, and a constant fraction of drug is eliminated per unit time. This pattern best represents which type of elimination kinetics?
In the Ann Arbor staging of Hodgkin lymphoma, a mediastinal mass is designated “bulky” (the X modifier) when its maximum width exceeds what proportion of the intrathoracic diameter on chest radiograph?
What is the specific antidote used in acute opioid (e.g. heroin, morphine) poisoning?
According to the AAST (American Association for the Surgery of Trauma) Colon Injury Scale, a laceration involving more than 50% of the bowel circumference (without transection) corresponds to which grade?
A trauma patient opens his eyes only to painful stimulus, makes incomprehensible sounds, and localises to pain. What is his total Glasgow Coma Scale (GCS) score?
In Bacillus anthracis, the poly-D-glutamic acid (poly-\(\gamma\)-D-glutamate) capsule is encoded by which plasmid?
Which of the following is a novel (newer) antidepressant that acts as a serotonin partial agonist and reuptake inhibitor (SPARI)?
A phenotypic female presents with primary amenorrhoea, an absent uterus, normally developed breasts and sparse/absent pubic and axillary hair. What is the most likely diagnosis?
The clinical photograph and slit-lamp image show iris hamartomas (Lisch nodules) with skin findings in a child with neurofibromatosis type 1 (NF1). Which cutaneous lesion is the earliest and most characteristic feature of NF1?
The photograph shows a permanent tattoo on the skin. In which layer of the skin is the tattoo pigment chiefly deposited and retained?
An infant girl shows normal early development followed by regression of acquired milestones at around 6-18 months, with deceleration of head growth and loss of purposeful hand use replaced by stereotyped hand-wringing movements. The most likely diagnosis is:
Which adverse effect is most characteristically associated with the antiepileptic drug lamotrigine?
If X percent of stroke in a population is attributable to hypertension, and removing hypertension from the population would prevent this proportion of strokes, this scenario is an example of:
In a meta-analysis, assessing heterogeneity (e.g. using the \(I^2\) statistic or Cochran's Q test):