List of top Questions asked in GAT-B- 2022

In Michaelis-Menten kinetics to increase the reaction velocity by 9 fold from 10% of $V_{max}$ to 90% of $V_{max}$ the substrate concentration has to increase by:

Match items in List I with items in List II
List I: A. Rickettsia prowazekii, B. Variola major, C. Varicella zoster Virus, D. Borrelia recurrentis
List II: I. Relapsing fever, II. Epidemic typhus, III. Small pox, IV. Shingles

For a batch microbial process the specific rate of substrate utilization is $0.25$ $h^{-1}$ and specific product formation rate is $0.20$ $h^{-1}$. The yield of product based on substrate consumed ($Y_{p/s}$) will be:

Match List I with List II - Match the industrial application of the following enzymes:
List I: A. Penicillinase, B. Pectinase, C. Trypsin, D. Renin
List II: I. Pharmaceutical, II. Leather, III. Wine, IV. Dairy

Match the coefficients in List I with their corresponding downstream processing steps in List II.
List I: A. Sedimentation, B. Partition, C. Rejection
List II: I. Aqueous two-phase extraction, II. Ultrafiltration, III. Dialysis, IV. Centrifugation

In animal cell culture, a $CO_{2}$ enriched atmosphere in the incubation chamber is used:

The growth pattern that you will obtain for a media containing two different carbon sources one of which is preferentially utilized will be a:

Which of the following describes cyclin-dependent kinase (Cdk)?
A. Cdk is inactive in the presence of cyclin
B. Cdk is present throughout the cell cycle
C. Cdk is an enzyme that attaches phosphate groups to other proteins

Arrange the following in correct sequence of steps in erythrocytic cycle of malarial parasite.
A. Parasite feeds on hemoglobin
B. Parasite forms a schizont
C. Nucleus moves to one side
D. Food vacuole increases in size
E. Haemozoin granules are formed

Once the cell passes the G1 checkpoint and enters S phase:

In power law model for fluid rheology, if the flow behavior index (n) is $<$1, then with increase in shear stress, the apparent viscosity:

The probability of mutation in a base-pair per round of replication is $5 \times 10^{-10}$ and the genome length of bacteria is 5 Mb. The number of bacterial cells required so that there is one mutation on an average per replication cycle is:

The fractional conversion from an immobilized enzyme continuous stirred tank reactor under steady state operation increases with an increase in agitation speed. This behavior can be attributed to:

The rate of sedimentation of a particle is dependent on the:

Immobilization of enzymes:
A. increases the specificity of the enzyme in batch reaction
B. leads to an increase in the apparent $K_{m}$
C. makes it unsuitable for its use in a continuous reactor system
D. decrease the operational cost of the industrial process

Which of the following represents the correct sequence of MAP kinase signal transduction pathway?
A. Ras, B. Raf, C. ERK, D. Mek

Resolution power of transmission electron microscope is of the sub nanometer level. This is because:

The hormone that activates the enzyme adenylate cyclase is:

The melting point of fatty acids in plant derived oils is influenced by:

Given below are two statements:
Statement I: Fatty acid synthase is an example of a tetramer of a multienzyme polypeptide.
Statement II: Each polypeptide harbors seven independent enzymatic functions.

In Michaelis-Menten kinetics what value of [S], as a fraction of $K_{m}$, is required to obtain a velocity equal to 80% $V_{max}$?

Major limitation of using NMR to determine protein structure is:

Which of the following is NOT a mucopolysaccharide?

Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R.
Assertion A: The major source of energy for the basic functioning of the cell is derived from oxidative metabolism.
Reason R: Mitochondria oxidize substrates to $CO_{2}$, transferring the high energy electron from molecular oxygen to glucose.

Which one of the following are Professional Antigen Presenting Cells?