Question:
Which of the following is the most active form of Estrane:
Which of the following is the most active form of Estrane:
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Estradiol is the "Gold Standard" of estrogen potency.
Updated On: May 25, 2026
- Estrone
- Estradiol
- Progesterone
- Androgen
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The Correct Option is B
Solution and Explanation
Step 1: Concept
Estrane is the C18 steroid nucleus that forms the structural basis for estrogens.
Step 2: Meaning
Activity refers to the biological potency and binding affinity to estrogen receptors in the body.
Step 3: Analysis
Estradiol (17$\beta$-estradiol) is the primary female sex hormone. It is significantly more potent than its metabolites, estrone and estriol. Progesterone and Androgens belong to different steroid nuclei (Pregnane and Androstane).
Step 4: Conclusion
Estradiol is the most physiologically active natural estrogen. Final Answer: (B)
Estrane is the C18 steroid nucleus that forms the structural basis for estrogens.
Step 2: Meaning
Activity refers to the biological potency and binding affinity to estrogen receptors in the body.
Step 3: Analysis
Estradiol (17$\beta$-estradiol) is the primary female sex hormone. It is significantly more potent than its metabolites, estrone and estriol. Progesterone and Androgens belong to different steroid nuclei (Pregnane and Androstane).
Step 4: Conclusion
Estradiol is the most physiologically active natural estrogen. Final Answer: (B)
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