Question:
Buffer most commonly used in ophthalmic preparation as
Buffer most commonly used in ophthalmic preparation as
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Tears are neutral; Phosphate buffers help keep them that way.
Updated On: May 25, 2026
- Lactate buffer
- Citrate buffer
- Phosphate buffer
- Acetate buffer
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The Correct Option is C
Solution and Explanation
Step 1: Concept
Ophthalmic preparations must be buffered to a pH that is comfortable for the eye and maintains drug stability.
Step 2: Meaning
The ideal pH for eye drops is close to the pH of lacrimal fluid (tears), which is about 7.4.
Step 3: Analysis
Phosphate buffers (like Sorensen's phosphate buffer) are frequently used because they have high buffering capacity near the physiological pH of the eye and are well-tolerated.
Step 4: Conclusion
Phosphate buffer is the most standard choice for ophthalmic formulations. Final Answer: (C)
Ophthalmic preparations must be buffered to a pH that is comfortable for the eye and maintains drug stability.
Step 2: Meaning
The ideal pH for eye drops is close to the pH of lacrimal fluid (tears), which is about 7.4.
Step 3: Analysis
Phosphate buffers (like Sorensen's phosphate buffer) are frequently used because they have high buffering capacity near the physiological pH of the eye and are well-tolerated.
Step 4: Conclusion
Phosphate buffer is the most standard choice for ophthalmic formulations. Final Answer: (C)
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