Step 1: Recall the two arms of immunity:
Humoral immunity depends on antibodies in body fluids. Cell-mediated immunity depends on T cells.
Antibody production belongs to the humoral arm.
Step 2: Identify the cell:
B-lymphocytes, on meeting an antigen, divide and form plasma cells and memory cells.
Plasma cells release large amounts of antibodies. So B-lymphocytes are the antibody producers.
Step 3: Why the others are wrong:
Macrophages engulf antigens and present them. They do not make antibodies.
Helper T cells help B cells to make antibodies by releasing signals, but they do not make antibodies themselves.
Cytotoxic T cells kill infected or foreign cells directly.
Final Answer:
B-lymphocytes produce antibodies. This is option (D).