Question:

Which of the following is the least abundant immunoglobulin class in a normal adult?

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• IgG $>$ IgA $>$ IgM $>$ IgD $>$ IgE
• IgE is least abundant but important in allergy
Updated On: May 13, 2026
  • IgG
  • IgE
  • IgM
  • IgA
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The Correct Option is B

Solution and Explanation

Concept: Different immunoglobulins are present in varying concentrations in the blood:
IgG: Most abundant
IgA: Second most abundant (especially in secretions)
IgM: Present in moderate amounts
IgE: Present in very low concentration

Step 1:
Comparing immunoglobulin levels.

• IgG → Highest
• IgA → High
• IgM → Moderate
• IgE → Lowest

Step 2:
Selecting the correct answer.
Thus, the least abundant immunoglobulin is IgE.
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