Question:
Taxol is primarily semi-synthesized from which of the following precursors:
Taxol is primarily semi-synthesized from which of the following precursors:
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Taxol starts with 10-DAB (10-Deacetylbaccatin III) for semi-synthesis.
Updated On: May 25, 2026
- 10-Deacetylbaccatin III
- Geranyl geranyl diphosphate
- 7-$\beta$-Xylosyl-10-deacetyltaxol
- Taxadiene
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The Correct Option is A
Solution and Explanation
Step 1: Concept
Taxol (Paclitaxel) is an anticancer drug originally isolated from the bark of the Pacific Yew tree.
Step 2: Meaning
Semi-synthesis is a chemical process that uses a natural precursor to create a complex drug, reducing the need for destructive harvesting of rare trees.
Step 3: Analysis
10-Deacetylbaccatin III (10-DAB) is found in the needles of the European Yew (Taxus baccata). It serves as the primary starting material for the commercial semi-synthesis of Taxol.
Step 4: Conclusion
10-Deacetylbaccatin III is the most important precursor for industrial Taxol production. Final Answer: (A)
Taxol (Paclitaxel) is an anticancer drug originally isolated from the bark of the Pacific Yew tree.
Step 2: Meaning
Semi-synthesis is a chemical process that uses a natural precursor to create a complex drug, reducing the need for destructive harvesting of rare trees.
Step 3: Analysis
10-Deacetylbaccatin III (10-DAB) is found in the needles of the European Yew (Taxus baccata). It serves as the primary starting material for the commercial semi-synthesis of Taxol.
Step 4: Conclusion
10-Deacetylbaccatin III is the most important precursor for industrial Taxol production. Final Answer: (A)
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