Question:
Match the following drugs with their mechanism of action: (A) Sumatriptan, (B) Ketanserin, (C) Ondansetron, (D) Cisapride.
Match the following drugs with their mechanism of action: (A) Sumatriptan, (B) Ketanserin, (C) Ondansetron, (D) Cisapride.
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Ondansetron (3 letters in 'set') = $5-HT_{3}$; Sumatriptan (1st choice for migraine) = $5-HT_{1}$.
Updated On: May 25, 2026
- A (I), B (II), C (III), D (IV)
- A (II), B (I), C (III), D (IV)
- A (III), B (IV), C (II), D (I)
- A (IV), B (II), C (III), D (I)
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The Correct Option is C
Solution and Explanation
Step 1: Concept
This involves identifying the specific receptor targets for different serotonin (5-HT) related drugs.
Step 2: Meaning
Agonists activate receptors, while antagonists block them.
Step 3: Analysis
Sumatriptan is a $5-HT_{1B/1D}$ agonist used for migraines. Ketanserin is a $5-HT_{2}$ antagonist used in hypertension. Ondansetron is a $5-HT_{3}$ antagonist used as an antiemetic. Cisapride is a $5-HT_{4}$ agonist used for gastric motility.
Step 4: Conclusion
Matching these gives: A-III, B-IV, C-II, D-I. Final Answer: (C)
This involves identifying the specific receptor targets for different serotonin (5-HT) related drugs.
Step 2: Meaning
Agonists activate receptors, while antagonists block them.
Step 3: Analysis
Sumatriptan is a $5-HT_{1B/1D}$ agonist used for migraines. Ketanserin is a $5-HT_{2}$ antagonist used in hypertension. Ondansetron is a $5-HT_{3}$ antagonist used as an antiemetic. Cisapride is a $5-HT_{4}$ agonist used for gastric motility.
Step 4: Conclusion
Matching these gives: A-III, B-IV, C-II, D-I. Final Answer: (C)
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