List of top Biochemistry Questions

Which phase of cell cycle is the shortest phase in terms of time?

Absorption of Vitmain B₁₂ is facilitated by

An enzyme (E) catalyzes the biochemical reaction \(A \rightarrow B\) with \(k_{\text{cat}}=500~\text{s}^{-1}\). If the initial reaction velocity \((V_0)\) is \(10~\mu\text{M}\cdot\text{s}^{-1}\) at the total enzyme concentration \([E_t]=30~\text{nM}\) and substrate concentration \([A]=40~\mu\text{M}\), the value of \(K_m\) (in \(\mu\text{M}\)) is ________________.

The number of different possible ways of forming five intramolecular disulfide bonds with ten cysteine residues of a protein is ________________.

Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with

A patient presenting with bleeding gums and easy bruisability was diagnosed with scurvy. This is due to

A child presents with bone pain and hepatosplenomegaly. A trephine biopsy and aspirate show the following finding. Which of the following is the most likely enzyme deficient in this condition?

A child presents with mental retardation, bone pain, and inability to walk. On funduscopic examination, a cherry red spot is seen. There is no organomegaly. What is the most likely diagnosis?

A child presents with thinning of hair and scaling of the scalp. On taking further history, it is found that she consumes raw eggs in her diet regularly. The given manifestations are due to the deficiency of which of the following vitamins?

An infant is brought by his parents with complaints that his urine turns black on standing. Which of the following metabolic disorders is likely?

Which of the following is seen in low insulin: glucagon ratio?

A child presents with erythematous scaly patches in the perioral region, mucosal ulcers, and impaired epithelial wound healing. The most likely mineral deficiency associated with this condition is?

A chronic alcoholic patient is diagnosed with gouty arthritis. What biochemical changes will be seen in this patient?

A child was bought with pedal edema and cheilosis. Cardiomegaly was present. What is the vitamin deficiency associated with this clinical presentation?

A 4-year-old child presents with easy fatigability. The mother also complains that the child has increased hunger between meals, which is relieved after food. Liver examination revealed no glycogen. The enzyme most likely deficient is?

A chronic alcoholic patient presented to the casualty with confusion, ataxia, and painful eye movements. What could be the vitamin deficiency seen in this patient?

A family consumes only polished rice. Which of the following combinations of vitamin deficiency and enzymatic defect will be present in this family?

A young boy presents to the OPD with hypoglycemia and muscle cramps, on exertion or while playing. Then he becomes normal after resting for a while. These episodes are recurrent after a period of activity. He has decreased serum lactate and glucose levels. Which of the following diseases is he most likely to be suffering from?

A patient presented with diarrhea, dermatitis, and dementia. Which of the following vitamin deficiencies would you suspect in this patient?

Which of the following clotting factors is needed for gamma-glutamyl carboxylase?

The melting point of fatty acids in plant derived oils is influenced by:

Which one of the following are Professional Antigen Presenting Cells?

Which of the following amino acids are both glucogenic and ketogenic?
A. Isoleucine, B. Serine, C. Tryptophan, D. Proline, E. Phenylalanine

The primary function of the class I and class II MHC molecules is:

NK cells are immunologically significant as they recognize and kill: