- Prokaryotes have a single RNA polymerase.
- Eukaryotes have three RNA polymerases: RNA polymerase I, II, and III.
- Prokaryotes rely on a single RNA polymerase for synthesizing all types of RNA (mRNA, tRNA, and rRNA).
- Eukaryotes have specialized RNA polymerases:
- RNA polymerase I synthesizes rRNA.
- RNA polymerase II synthesizes mRNA.
- RNA polymerase III synthesizes tRNA and some small RNAs.
}