Question:
Which of the following statements are correct in respect to pyridoxine (vitamin B6)?
(A). Pyridoxine is found in cells in the active form as pyridoxal phosphate (PLP)
(B). Act as a coenzyme in various metabolic reactions involving carbohydrates, fats, and proteins
(C). Pyridoxine is unstable in acidic medium and relatively stable in alkaline medium
(D). Vitamin B-6 deficiency increases urinary oxalate formation
Choose the correct answer from the options given below:
Which of the following statements are correct in respect to pyridoxine (vitamin B6)?
(A). Pyridoxine is found in cells in the active form as pyridoxal phosphate (PLP)
(B). Act as a coenzyme in various metabolic reactions involving carbohydrates, fats, and proteins
(C). Pyridoxine is unstable in acidic medium and relatively stable in alkaline medium
(D). Vitamin B-6 deficiency increases urinary oxalate formation
Choose the correct answer from the options given below:
(A). Pyridoxine is found in cells in the active form as pyridoxal phosphate (PLP)
(B). Act as a coenzyme in various metabolic reactions involving carbohydrates, fats, and proteins
(C). Pyridoxine is unstable in acidic medium and relatively stable in alkaline medium
(D). Vitamin B-6 deficiency increases urinary oxalate formation
Choose the correct answer from the options given below:
Show Hint
Most water-soluble vitamins (such as B6 and C) are chemically more stable in acidic environments than in alkaline ones.
Updated On: Jul 10, 2026
- (A), (B) and (C) only.
- (A), (C) and (D) only.
- (A), (B), and (D) only.
- (B), (C), and (D) only.
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Vitamin B6 exists as a group of closely related water-soluble vitamers: pyridoxine, pyridoxal, and pyridoxamine, which are active in metabolic pathways.
Step 2: Detailed Explanation:
- Statement (A): Within cells, B6 vitamers are phosphorylated into the active coenzyme form, pyridoxal phosphate (PLP). (Statement A is correct)
- Statement (B): PLP acts as a coenzyme in transamination, decarboxylation, and deamination reactions, which are vital for the metabolism of carbohydrates, lipids, and amino acids. (Statement B is correct)
- Statement (C): Pyridoxine is relatively stable in acidic environments but is highly unstable and sensitive in alkaline media, especially when exposed to light or heat. (Statement C is incorrect)
- Statement (D): A deficiency in Vitamin B6 impairs the PLP-dependent transamination of glyoxylate, causing its accumulation and subsequent conversion into oxalate, leading to increased urinary oxalate levels. (Statement D is correct)
Therefore, statements (A), (B), and (D) are correct.
Step 3: Final Answer:
The correct statements are (A), (B), and (D), representing Option C.
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