Question

Which of the following is a function of collagen in human body?

• A. Providing strength to our bones.
• B. Production of hormones.
• C. Transport of oxygen to tissues.
• D. Secretion of digestive enzymes.

Hint:

Scurvy is caused by Vitamin C deficiency. Vitamin C (ascorbate) is a co-factor for prolyl hydroxylase, an enzyme that hydroxylates proline residues in collagen to stabilize its triple-helix structure.

Answer 1

The Correct Option is A

Step 1: Concept
Collagen is the most abundant structural protein in the human body, constituting about $25% - 35%$ of total protein content.

Step 2: Structural Properties
Collagen is a fibrous, triple-helical protein that exhibits immense tensile strength. It is a major component of extracellular matrix networks in connective tissues, including cartilage, tendons, ligaments, skin, and bones.

Step 3: Functional Mapping
- In bones, collagen fibers form a flexible organic scaffold that is mineralized with calcium hydroxyapatite crystals, providing high tensile strength and resilience (preventing brittleness).
- Hormones are produced by endocrine cells (mostly peptide/lipid messengers, not collagen).
- Oxygen transport is performed by hemoglobin.
- Digestive enzymes are globular catalytic proteins.


Step 4: Conclusion
Hence, collagen's primary function is structural support, such as providing tensile strength to bones, matching option (A). Final Answer: (A)