Question:
Which is the site of attachment of spindle fibres to chromosomes during metaphase of mitosis?
Which is the site of attachment of spindle fibres to chromosomes during metaphase of mitosis?
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Centromere holds chromatids; kinetochore is the actual site where spindle fibres attach.
Updated On: May 13, 2026
- Kinetoplast of chromosomes
- Kinetoplast and chromatid arms
- Sister chromatids of chromosomes
- Kinetochores of chromosomes
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The Correct Option is D
Solution and Explanation
Concept:
During mitosis, spindle fibers attach to chromosomes at a specific protein structure called the kinetochore, which is located on the centromere.
Step 1: Understand chromosome structure.
Each chromosome has:
• Centromere
• Kinetochores (protein complexes on centromere)
Step 2: Attachment of spindle fibres.
Spindle fibers from opposite poles attach to: \[ \text{Kinetochores of sister chromatids} \]
Step 3: Analyze options.
• Kinetoplast → unrelated (found in some protozoa)
• Chromatid arms → not attachment site
• Sister chromatids → not specific structure
• Kinetochores → correct
Step 4: Final conclusion.
Thus, spindle fibres attach at: \[ Kinetochores of chromosomes \]
Step 1: Understand chromosome structure.
Each chromosome has:
• Centromere
• Kinetochores (protein complexes on centromere)
Step 2: Attachment of spindle fibres.
Spindle fibers from opposite poles attach to: \[ \text{Kinetochores of sister chromatids} \]
Step 3: Analyze options.
• Kinetoplast → unrelated (found in some protozoa)
• Chromatid arms → not attachment site
• Sister chromatids → not specific structure
• Kinetochores → correct
Step 4: Final conclusion.
Thus, spindle fibres attach at: \[ Kinetochores of chromosomes \]
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