Question

Which of the following cell types has the highest surface area to volume ratio?

• A. RBC
• B. Fibroblast
• C. Keratinocyte
• D. Hepatocyte

Hint:

Cells with a high surface area to volume ratio, like RBCs, are more efficient in diffusion and transport of substances across their membranes.

Answer 1

The Correct Option is A

Step 1: Understand what surface area to volume ratio means 
The surface area to volume ratio (SA:V) is an important factor in determining the efficiency of material exchange (like oxygen, nutrients, and waste) across the cell membrane. 
Step 2: Consider the structure of RBCs 
Red Blood Cells (RBCs) are biconcave disc-shaped, which gives them a large surface area relative to their volume. This feature allows for rapid gas exchange, especially oxygen and carbon dioxide. 
Step 3: Compare with other cell types 
Fibroblasts are elongated cells involved in structural frameworks. 
Keratinocytes are large, flat cells forming the outer skin layer. 
Hepatocytes are large polygonal liver cells with high metabolic activity. None of these have a surface area to volume ratio higher than RBCs.