Question:
The primary enzyme responsible for the rapid and accurate replication of the genome in E. coli is:
The primary enzyme responsible for the rapid and accurate replication of the genome in E. coli is:
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Think "III" for "Main"—Pol III does the heavy lifting in DNA replication.
Updated On: May 14, 2026
- DNA Pol V
- DNA Pol II
- DNA Pol III
- DNA Pol IV
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The Correct Option is C
Solution and Explanation
Step 1: Concept
Prokaryotes use multiple DNA polymerases, each with distinct roles.
Step 2: Meaning
Replication requires high processivity (speed) and high fidelity (accuracy).
Step 3: Analysis
DNA Pol I is for primer removal and repair. DNA Pol II, IV, and V are primarily for DNA repair. DNA Pol III is the main replicative enzyme complex.
Step 4: Conclusion
DNA Pol III performs the bulk of DNA synthesis during replication in E. coli. Final Answer: (C)
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