Question:

RNAi or post-transcriptional gene silencing is a conserved biological response to the presence of:

Show Hint

RNAi is the cell's defense against dsRNA (often from viruses).
Updated On: May 14, 2026
  • ssDNA
  • dsDNA
  • ssRNA
  • dsRNA
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The Correct Option is D

Solution and Explanation


Step 1: Concept

RNA interference (RNAi) is a regulatory mechanism that degrades specific mRNA molecules.

Step 2: Meaning

Post-transcriptional silencing means the gene is transcribed into mRNA, but the mRNA is destroyed before it can be translated.

Step 3: Analysis

The process is triggered by double-stranded RNA (dsRNA). An enzyme called Dicer cleaves the dsRNA into small interfering RNAs (siRNAs). These are incorporated into the RISC complex, which then identifies and degrades complementary single-stranded mRNA.

Step 4: Conclusion

Double-stranded RNA (dsRNA) is the primary trigger for the RNAi pathway. Final Answer: (D)
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