Question:
Single Nucleotide Polymorphisms can occur:
Single Nucleotide Polymorphisms can occur:
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There are approximately 10 million SNPs in the human genome. They are highly valuable as genetic markers to map complex diseases and study evolutionary lineages.
Updated On: Jun 19, 2026
- only in the coding regions of a genome.
- only in the non-coding regions of a genome.
- in both coding and non-coding regions of a genome.
- in mitochondrial DNA only
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The Correct Option is C
Solution and Explanation
Step 1: Concept
A Single Nucleotide Polymorphism (SNP) is a variation in a single DNA base pair (A, T, C, or G) occurring at a specific locus in the genome, present in at least $1%$ of a population.
Step 2: Genomic Distribution
SNPs are the most common type of genetic variation among people. They are distributed throughout the entire genome:
1. Coding regions: Can alter amino acid sequences (missense/nonsense mutations) or remain silent (synonymous).
2. Non-coding regions: Can occur in introns, intergenic zones, promoters, or enhancers, potentially altering gene splicing or transcriptional regulation levels.
Step 3: Conclusion
Because SNPs occur throughout all nuclear and organelle DNA sequences, they can occur in both coding and non-coding regions of a genome, matching option (C). Final Answer: (C)
A Single Nucleotide Polymorphism (SNP) is a variation in a single DNA base pair (A, T, C, or G) occurring at a specific locus in the genome, present in at least $1%$ of a population.
Step 2: Genomic Distribution
SNPs are the most common type of genetic variation among people. They are distributed throughout the entire genome:
1. Coding regions: Can alter amino acid sequences (missense/nonsense mutations) or remain silent (synonymous).
2. Non-coding regions: Can occur in introns, intergenic zones, promoters, or enhancers, potentially altering gene splicing or transcriptional regulation levels.
Step 3: Conclusion
Because SNPs occur throughout all nuclear and organelle DNA sequences, they can occur in both coding and non-coding regions of a genome, matching option (C). Final Answer: (C)
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