Question

Select the \(\textit{incorrect}\) match from the following:
 

• A. 45 + XX & \(\text{Broad palm with characteristic palm crease} \)
• B. 44 + XXY & \(\text{Overall feminine development} \)
• C. 44 + XO & \(\text{Sterile females as ovaries are rudimentary} \)
• D. 44 + XY & \(\text{Normal male} \)

Hint:

Karyotype tips: 44 + XO: Turner Syndrome (Infertile females). 44 + XXY: Klinefelter Syndrome (Affects males with partial masculine development). 45 + XX/XY: Down Syndrome.

Answer 1

The Correct Option is B

(A) 45 + XX: This refers to Down Syndrome, which is characterized by distinct physical traits such as broad palms and palm creases.
(B) 44 + XXY: Incorrect. This karyotype represents Klinefelter Syndrome, which affects males and results in partial masculine development, not feminine characteristics.
(C) 44 + XO: This refers to Turner Syndrome, where females are infertile due to underdeveloped ovaries.
(D) 44 + XY: This corresponds to normal males.