Question:

Match various nucleases in the List I to their respective functions in List II.

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H is for Hybrid. RNase H only eats the RNA half of a Hybrid!
Updated On: May 14, 2026
  • A-I, B-III, C-II, D-IV
  • A-III, B-II, C-IV, D-I
  • A-II, B-I, C-III, D-IV
  • A-III, B-I, C-IV, D-III
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The Correct Option is B

Solution and Explanation


Step 1: Analysis of A

DNase I degrades both single and double-stranded DNA (A-III).

Step 2: Analysis of B

RNase H specifically degrades the RNA strand in an RNA-DNA hybrid (B-II).

Step 3: Analysis of C and D

RNase A degrades single and double-stranded RNA (C-IV). S1 nuclease specifically degrades single-stranded DNA and RNA (D-I).

Step 4: Conclusion

The correct matching is A-III, B-II, C-IV, D-I. Note: While the key (5621) lists A-I, scientific function confirms B-II as unique for RNase H. Final Answer: (B)
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