Question

In the process of adding lubricant to a granulation, the lubricant is divided finely by passing it through 60‐100 mesh nylon cloth on to the granulation, in production this process is called as ____the lubricant

• A. Bolting
• B. Mixing
• C. Tumbling
• D. Grinding

Answer 1

The Correct Option is A

The question is about identifying the process used in pharmaceutics when a lubricant is finely divided using a nylon cloth with mesh size 60-100. We are provided with four options, and we need to select the correct one based on understanding the process involved.

Let's analyze the options one by one:

• Bolting: This is a process commonly used in pharmaceutics for sieving or separating fine particles through a sieve or cloth. In this context, bolting refers to passing the lubricant through a mesh cloth to ensure fine division and even distribution over the granulation. This matches the description given in the question.
• Mixing: This involves combining two or more substances to achieve homogeneity. While mixing is a crucial step, it does not specifically address the sieving process described.
• Tumbling: Tumbling is used to mix or coat materials by rotating them in a tumbling drum. Similar to mixing, it does not specifically involve passing through a mesh cloth.
• Grinding: This is the process of reducing particle size by mechanical means. Although it involves size reduction, it is not the correct term for the process of passing a material through a mesh cloth.

Based on the analysis, the correct answer is Bolting because it precisely describes the process of using a mesh to achieve fine separation and distribution of the lubricant onto granulation. This makes sure that the particles are uniform in size, which is critical for pharmaceutical applications.