Question:
Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: In the manufacturing of glycero‐gelatin suppositories, overfilling of mould is necessary.
Reason R: Glycero‐gelatin bases contract very little on cooling and the excess cannot be neatly removed.
In light of the above statements, choose the correct answer from the options given below
Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: In the manufacturing of glycero‐gelatin suppositories, overfilling of mould is necessary.
Reason R: Glycero‐gelatin bases contract very little on cooling and the excess cannot be neatly removed.
In light of the above statements, choose the correct answer from the options given below
Assertion A: In the manufacturing of glycero‐gelatin suppositories, overfilling of mould is necessary.
Reason R: Glycero‐gelatin bases contract very little on cooling and the excess cannot be neatly removed.
In light of the above statements, choose the correct answer from the options given below
Updated On: Mar 5, 2026
- Both A and R are true and R is the correct explanation of A
Both A and R are true and R is the correct explanation of A
- A is true but R is false
- A is false but R is true
Show Solution
Verified By Collegedunia
The Correct Option is D
Solution and Explanation
To answer the question about the assertion and reason provided, let's analyze both statements:
-
Assertion A: "In the manufacturing of glycero-gelatin suppositories, overfilling of mould is necessary."
- The manufacturing process of glycero-gelatin suppositories involves filling moulds to form the shape of the suppository. Overfilling is usually not required as it leads to wastage and can create issues in solidifying evenly.
- Generally, proper filling without overfilling ensures that the suppository forms correctly and the process is efficient.
- Therefore, Assertion A is not true for the manufacturing of glycero-gelatin suppositories.
-
Reason R: "Glycero-gelatin bases contract very little on cooling and the excess cannot be neatly removed."
- It is known that glycero-gelatin bases have minimal contraction upon cooling, which is a valid statement about their physical properties.
- Due to this minimal contraction, managing excess material after filling can be challenging since it doesn't shrink significantly to allow tidy removal.
- Thus, Reason R is a true statement concerning glycero-gelatin bases.
From the above analysis, we conclude:
- Assertion A is false because overfilling is not necessary in manufacturing if managed properly.
- Reason R is true as it accurately describes the contraction characteristics of glycero-gelatin.
Therefore, the correct answer is: A is false but R is true.
Was this answer helpful?
0
0
Top GPAT Pharmaceutics Questions
- Which of the following is an example of a thermosetting plastic material?
- Which of the following vehicles (not required to be sterile, but must be pyrogen free) is intended to be used in the manufacture of injectable products to be sterilized after preparation?
A typical skin cream consisting of stearic acid, potassium hydroxide, glycerin, water, preservative and perfume, would be commonly known as:
- Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: The pressure filling method for filling pharmaceutical aerosol is usually preferred over cold filling method
Reason R: Because with pressure filling method high production speed can be achieved and less propellant is lost.
In light of the above statements, choose the correct answer from the options given below - In the process of sugar coating, to prevent moisture penetration into the tablet core, which one of the following step is performed?
View More Questions
Top GPAT Suppositories Questions
- When six suppositories containing 20 percent of morphine hydrochloride in Theobroma oil are to be prepared, which of the following statement is correct? (Given: Displacement value of morphine hydrochloride is 1.5; weight of each suppository is 1g)
- In Bismuth subgallate suppositories B.P.C, when no strength of the drug is specified, B.P.C directs _________ bismuth subgallate per suppository
- The liquefaction time of cocoa butter of hydrogenated vegetable oil based suppositories is
Top GPAT Questions
- Match the symbols in the List I with the terms used in the List II of conductance measurements, and
List I
SymbolsList II
TermsA \(\Omega^{-1}\) I Specific conductance B \(∧\) II Electrical conductance C k III Specific resistance D \(\rho\) IV Equivalent conductance
Choose the correct answer from the options given below: - Cottrell’s method is used for the measurement of:
- Match the statements in List I with their correct answers in List II, respectively, in respect to modified 1st law of thermodynamics, and
List I
List II
A Constant heat (q = 0) I Isothermal B Reversible process at constant temperature (dT = 0) II Isometric C Constant volume (dV = 0) III Adiabatic D Constant pressure (dP = 0) IV Isobar
Choose the correct answer from the options given below: - Boric acid with molecular weight 61.83 was partitioned between water and amyl alcohol at 25 °C. The amount of boric acid was determined to be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The partition coefficient of boric acid between water and amyl alcohol, when calculated at molar concentration for each of the solution, is:
- Drugs ‘A’, ‘B’ and ‘C’ follow zero order, first order and second order degradation kinetics, respectively, but have the same rate constant. Which of the following statement is true in this respect:
View More Questions