Question:

Given below are two statements about hnRNA processing:
Statement I: Capping occurs by addition of methyl adenosine triphosphate to the 5' end.
Statement II: During tailing, about 200-300 adenylate residues are added to its 3' end.

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Capping uses Guanosine; Tailing uses Adenosine. (G at the start, A at the end).
Updated On: May 14, 2026
  • Both Statement I and Statement II are true.
  • Both Statement I and Statement II are false.
  • Statement I is true but Statement II is false.
  • Statement I is false but Statement II is true.
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The Correct Option is D

Solution and Explanation


Step 1: Concept

Processing of heterogeneous nuclear RNA (hnRNA) into mature mRNA involves capping, tailing, and splicing.

Step 2: Meaning

Capping happens at the 5' end, and tailing happens at the 3' end.

Step 3: Analysis

Statement I is false because the cap is 7-methylguanosine triphosphate (m7G), not adenosine. Statement II is true: polyadenylation adds a "Poly-A tail" of several hundred adenylate residues to protect the mRNA.

Step 4: Conclusion

As the identity of the capping nucleotide is wrong but the tailing description is correct, Option D is the answer. Final Answer: (D)
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