Question:
G Protein receptor activation follows the sequence:
G Protein receptor activation follows the sequence:
Show Hint
cAMP is the "second messenger" that must be formed before kinases can be activated.
Updated On: May 28, 2026
- A, B, C, D
- D, A, B, C
- B, A, C, D
- D, A, C, B
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Concept
This describes the signal transduction pathway of $G_s$-coupled receptors.
Step 2: Meaning
Extracellular signals are converted into intracellular actions through a cascade of molecular events.
Step 3: Analysis
Activation of the receptor stimulates adenylyl cyclase to convert ATP to Cyclic AMP (B). Increased cAMP activates Protein Kinase A (A). This leads to the release of calcium ions from intracellular stores (C) , which ultimately triggers the physiological response, such as muscle contraction (D).
Step 4: Conclusion
The logical sequence of activation is B-A-C-D.
Final Answer: (C)
This describes the signal transduction pathway of $G_s$-coupled receptors.
Step 2: Meaning
Extracellular signals are converted into intracellular actions through a cascade of molecular events.
Step 3: Analysis
Activation of the receptor stimulates adenylyl cyclase to convert ATP to Cyclic AMP (B). Increased cAMP activates Protein Kinase A (A). This leads to the release of calcium ions from intracellular stores (C) , which ultimately triggers the physiological response, such as muscle contraction (D).
Step 4: Conclusion
The logical sequence of activation is B-A-C-D.
Final Answer: (C)
Was this answer helpful?
0
0
Top CUET PG Pharmacy Questions
- Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: The presence of molecular forces produces a tendancy for individual solid particles to stick to each other and to other surface.
Reason R: Adhesion and cohesion can be considered as two aspects of particle aggregation.
In the light of the above statements, choose the most appropriate answer from the options given below: - Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: Immunoelectrophoresis or RIA is the best method for the quantification of IgE.
Reason R: Ordinary electrophoresis does not identify the subgroups of immunoglobulins IgG, IgA, IgM. IgE.
In the light of the above statements, choose the most appropriate answer from the options given below : - Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: The modified Noyes - Whitney equation states that larger the surface area of a drug, higher is the dissolution rate.
Reason R: the surface area increases with decreasing particle size.
In the light of the above statements, choose the most appropriate answer from the options given below - Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: Haloperidol is a preferred drug for acute schizophrenia and Huntington's disease.
Reason R: Parenteral administration by intramuscular route is possible in acute cases
In the light of the above statements, choose the most appropriate answer from the options given below: - Match List I with List II
List I
(Oral anti-diabetic Agents)List II
(Mechanism of Action)A. Voglibose I. AMP Activator B. Metformin II. K Channel blockers C. Tolbutamide III. \(\alpha\)-glucosidase Inhibitor D. Pioglitazone IV. PPAR-\(\gamma\) (gamma) activators
Choose the correct answer from the options given below:
View More Questions
Top CUET PG Pharmacology Questions
- Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI)?
- What is the mechanism of action for the drug Omeprazole?
- Which vitamin is essential for the synthesis of blood clotting factors?
- The proper sequence of phenomenon in percutaneous absorption via trans follicular route is:
- Match the LIST-I (Rate limiting step) with LIST-II (Drugs) in absorption: [H] {|l|l|} \multicolumn{1}{|c|}{LIST-I & \multicolumn{1}{c|}{LIST-II
\multicolumn{1}{|c|}{Rate limiting step & \multicolumn{1}{c|}{Drugs
A. Gastric emptying time & I. Insulin
B. Dissolution & II. Diltiazem
C. Permeability & III. Taxol
D. Case by case & IV. Nifedipine
View More Questions
Top CUET PG Questions
- Given below are two statements:
Statement I: For Plato the meaning of the word 'Justice' is basically a conception in the mind only.
Statement II: For Plato the meaning of the word 'Justice' is fixed, mind-independently
In the light of the above statements, choose the correct answer from the options given below: - What is the electron count of OS6CO182-?
- XeF4 hydrolysis gives A + B, HF, and Oxygen. Find A and B
- What is more basic in pyrol and pyridine?
- Hydrolysis of Al2C3, Be2?
View More Questions