Question:
Match the LIST-I (Rate limiting step) with LIST-II (Drugs) in absorption:
[H]
{|l|l|}
\multicolumn{1}{|c|}{LIST-I & \multicolumn{1}{c|}{LIST-II
\multicolumn{1}{|c|}{Rate limiting step & \multicolumn{1}{c|}{Drugs
A. Gastric emptying time & I. Insulin
B. Dissolution & II. Diltiazem
C. Permeability & III. Taxol
D. Case by case & IV. Nifedipine
Match the LIST-I (Rate limiting step) with LIST-II (Drugs) in absorption:
[H]
{|l|l|}
\multicolumn{1}{|c|}{LIST-I & \multicolumn{1}{c|}{LIST-II
\multicolumn{1}{|c|}{Rate limiting step & \multicolumn{1}{c|}{Drugs
A. Gastric emptying time & I. Insulin
B. Dissolution & II. Diltiazem
C. Permeability & III. Taxol
D. Case by case & IV. Nifedipine
\multicolumn{1}{|c|}{Rate limiting step & \multicolumn{1}{c|}{Drugs
A. Gastric emptying time & I. Insulin
B. Dissolution & II. Diltiazem
C. Permeability & III. Taxol
D. Case by case & IV. Nifedipine
Show Hint
Insulin is a large protein; its absorption is limited by how it crosses (Permeability).
Updated On: May 28, 2026
- A-I, B-IV, C-III, D-II
- A-III, B-IV, C-I, D-II
- A-II, B-IV, C-I, D-III
- A-II, B-III, C-I, D-IV
Show Solution
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The Correct Option is C
Solution and Explanation
Step 1: Concept
The rate-limiting step is the slowest part of the absorption process that dictates the overall rate of drug entry into the system.
Step 2: Meaning
A. Gastric emptying time affects drugs like Diltiazem. B. Dissolution is the bottleneck for poorly soluble drugs like Nifedipine. C. Permeability is the limit for large molecules like Insulin. D. Taxol has complex absorption (case by case).
Step 3: Analysis
Matching: A-II (Gastric Emptying-Diltiazem), B-IV (Dissolution-Nifedipine), C-I (Permeability-Insulin), and D-III (Case by case-Taxol).
Step 4: Conclusion
The correct match is A-II, B-IV, C-I, D-III.
Final Answer: (C)
The rate-limiting step is the slowest part of the absorption process that dictates the overall rate of drug entry into the system.
Step 2: Meaning
A. Gastric emptying time affects drugs like Diltiazem. B. Dissolution is the bottleneck for poorly soluble drugs like Nifedipine. C. Permeability is the limit for large molecules like Insulin. D. Taxol has complex absorption (case by case).
Step 3: Analysis
Matching: A-II (Gastric Emptying-Diltiazem), B-IV (Dissolution-Nifedipine), C-I (Permeability-Insulin), and D-III (Case by case-Taxol).
Step 4: Conclusion
The correct match is A-II, B-IV, C-I, D-III.
Final Answer: (C)
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