Question

__________drug is mostly considered as first-line therapy for uncomplicated urinary tract infection (UTI) in a young, non-pregnant woman.

• A. Gentamicin injection
• B. Nitrofurantoin
• C. Amoxicillin
• D. Ciprofloxacin

Hint:

Nitrofurantoin is commonly preferred for uncomplicated lower UTI because it achieves high urinary concentration.

Answer 1

The Correct Option is B

Concept:
Uncomplicated urinary tract infection means infection of the urinary tract in a healthy patient without major complications, structural abnormality, or pregnancy.

Step 1: Understanding uncomplicated UTI.
In young non-pregnant women, uncomplicated UTI is commonly caused by bacteria such as E. coli.

Step 2: First-line drug.
Nitrofurantoin is commonly used as first-line therapy for uncomplicated lower UTI because it concentrates well in urine.

Step 3: Why nitrofurantoin is suitable.
It acts mainly in the urinary tract and has good activity against common UTI pathogens.

Step 4: Checking other options.
Gentamicin injection is not used routinely for uncomplicated UTI.
Amoxicillin may have resistance problems.
Ciprofloxacin is effective but is usually reserved due to resistance and safety concerns.

Step 5: Final answer.
Therefore, nitrofurantoin is mostly considered first-line therapy. \[ \boxed{\text{Nitrofurantoin}} \]