Question

______ class of antihypertensive drugs is contraindicated due to teratogenic effects on the fetus in pregnant women with hypertension.

• A. Thiazide diuretics
• B. Beta blockers
• C. ACE inhibitors
• D. Calcium channel blockers

Hint:

ACE inhibitors are contraindicated in pregnancy because they can cause serious fetal toxicity.

Answer 1

The Correct Option is C

Concept:
Drug use during pregnancy requires special care because some drugs can harm the developing fetus.

Step 1: Understanding teratogenicity.
Teratogenic drugs are drugs that can cause fetal abnormalities when taken during pregnancy.

Step 2: ACE inhibitors in pregnancy.
ACE inhibitors are contraindicated in pregnancy because they can cause fetal kidney damage, oligohydramnios, skull defects, and other serious fetal problems.

Step 3: Examples of ACE inhibitors.
Common ACE inhibitors include:
• Enalapril
• Captopril
• Lisinopril
• Ramipril

Step 4: Checking other options.
Beta blockers and calcium channel blockers may be used carefully in selected cases.
Thiazide diuretics are not the classic answer for fetal teratogenic contraindication here.
ACE inhibitors are clearly contraindicated due to fetal toxicity.

Step 5: Final answer.
Therefore, ACE inhibitors are contraindicated in pregnant women with hypertension. \[ \boxed{\text{ACE inhibitors}} \]