Question:
Choose correct sequence of anesthetics in increasing order of their partition coefficients:
Choose correct sequence of anesthetics in increasing order of their partition coefficients:
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Lowest Blood/Gas = Fastest induction. Nitrous Oxide is always the fastest/least soluble in blood.
Updated On: May 28, 2026
- A, B, C, D
- A, C, D, B
- D, B, C, A
- D, C, B, A
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The Correct Option is D
Solution and Explanation
Step 1: Concept
The blood/gas partition coefficient determines the solubility of an inhalation anesthetic in blood and affects its rate of induction and recovery.
Step 2: Meaning
A higher partition coefficient means the drug is more soluble in blood, leading to a slower induction of anesthesia.
Step 3: Analysis
The standard blood/gas partition coefficients are approximately: Nitrous oxide (0.47) $<$ Sevoflurane (0.65) $<$ Enflurane (1.9) $<$ Halothane (2.4).
Step 4: Conclusion
The increasing order is Nitrous oxide (D), Sevoflurane (C), Enflurane (B), Halothane (A).
Final Answer: (D)
The blood/gas partition coefficient determines the solubility of an inhalation anesthetic in blood and affects its rate of induction and recovery.
Step 2: Meaning
A higher partition coefficient means the drug is more soluble in blood, leading to a slower induction of anesthesia.
Step 3: Analysis
The standard blood/gas partition coefficients are approximately: Nitrous oxide (0.47) $<$ Sevoflurane (0.65) $<$ Enflurane (1.9) $<$ Halothane (2.4).
Step 4: Conclusion
The increasing order is Nitrous oxide (D), Sevoflurane (C), Enflurane (B), Halothane (A).
Final Answer: (D)
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