Question

(b) “DNA replication is continuous and discontinuous on the two strands within the replication fork.” Explain with the help of a schematic representation.

Hint:

The semi-discontinuous replication mechanism ensures efficient and accurate duplication of genetic material.

Answer 1

- Leading strand: Synthesized continuously in the 5’ to 3’ direction towards the replication fork. 
- Lagging strand: Synthesized in short Okazaki fragments in the 5’ to 3’ direction away from the replication fork. These fragments are later joined by DNA ligase, ensuring the continuity of the strand.