List of top Questions asked in GPAT

A patient with pheochromocytoma is undergoing surgery and has not been administered with alpha receptor blocker. If he is administered with intravenous propranolol, then which of the following effects will be evident?

Regarding Bromocriptine, which of the following statement is TRUE‐ It is a relatively selective dopamine D2 agonist with prominent action
A. on pituitary lactotrophs (inhibit prolactin release) 
B. in striatum (antiparkinsonian) 
C. in CTZ (antiemetic) ATP γ K 5) 6) 7) 
D. as an adjunctive treatment for type 2 DM 
Choose the correct answer from the options given below:

Which of the following DRYERS is a "static bed dryer"?

Isobutane upon bromination under the influence of ultraviolet light at 127 °C affords the following major product:

Tropane nucleus is combination of

The ‘Up‐and‐Down’ method for a projected LD50 determination is described in the…..

Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: During the process of decompression in tablet manufacturing, expansion occurs in some tablet. 
Reason R: Expansion occurs in some tablet because of Plastic deformation that has occurred during compression process. 
In light of the above statements, choose the correct answer from the options given below

Cottrell’s method is used for the measurement of:

Boric acid with molecular weight 61.83 was partitioned between water and amyl alcohol at 25 °C. The amount of boric acid was determined to be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The partition coefficient of boric acid between water and amyl alcohol, when calculated at molar concentration for each of the solution, is:

Optically active mandelic acid can be synthesized from benzaldehyde in the presence of the enzyme:

Citric acid cycle is the final pathway during the oxidation of _______ .

Which one of the following is NOT a phospholipid?

Which of the following vehicles (not required to be sterile, but must be pyrogen free) is intended to be used in the manufacture of injectable products to be sterilized after preparation?

Match the symbols in the List I with the terms used in the List II of conductance measurements, and

List I Symbols		List II Terms
A	\(\Omega^{-1}\)	I	Specific conductance
B	\(∧\)	II	Electrical conductance
C	k	III	Specific resistance
D	\(\rho\)	IV	Equivalent conductance

Choose the correct answer from the options given below:

Drugs ‘A’, ‘B’ and ‘C’ follow zero order, first order and second order degradation kinetics, respectively, but have the same rate constant. Which of the following statement is true in this respect:

Match the statements in List I with their correct answers in List II, respectively, in respect to modified 1st law of thermodynamics, and

List I		List II
A	Constant heat (q = 0)	I	Isothermal
B	Reversible process at constant temperature (dT = 0)	II	Isometric
C	Constant volume (dV = 0)	III	Adiabatic
D	Constant pressure (dP = 0)	IV	Isobar

Choose the correct answer from the options given below:

Given below are the two statements
Statement I: Glucose‐6‐phosphate can be formed from glucose, but not from glycogen.
Statement II: Glucose‐1‐phosphate may be hydrolyzed to yield free glucose in liver.
Choose the most appropriate answer from the options given below:

All enzymes accelerate the reaction rates by______________ .

Heme is ____ .

Statement I: The problem of declining potency in an unstable preparation can be ameliorated by the addition of an excess or overage of the active ingredient.
Statement II: Overages, are added to pharmaceutical formulations to keep the content of the active ingredient well above the limit, compatible with therapeutic requirements, for a predetermined period of time

In the process of extraction, if maceration is accomplished by heating the drug and solvent in a close vessel, then this modification is known as _____

Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: The pressure filling method for filling pharmaceutical aerosol is usually preferred over cold filling method 
Reason R: Because with pressure filling method high production speed can be achieved and less propellant is lost. 
In light of the above statements, choose the correct answer from the options given below

Reason for the combination of Diphenoxylate (2.5 mg) + Atropine (0.025 mg) is to

Anthranilic acid is an immediate precursor in the formation of