Question

Wilson disease is due to excess of _______

• A. Copper
• B. Zinc
• C. Calcium
• D. Sodium

Hint:

Wilson disease is associated with copper accumulation, while copper deficiency is not the cause of this disease.

Answer 1

The Correct Option is A

Concept:
Wilson disease is a genetic disorder of copper metabolism. In this disease, copper is not properly excreted from the body.

Step 1: Normal copper metabolism.
Normally, excess copper is removed from the body through bile.

Step 2: What happens in Wilson disease?
In Wilson disease, copper accumulates in tissues because its excretion is defective.

Step 3: Organs affected.
Excess copper may accumulate mainly in:
• Liver
• Brain
• Eyes

Step 4: Clinical importance.
Copper accumulation can cause liver disease, neurological symptoms, and Kayser-Fleischer rings in the eyes.

Step 5: Final answer.
Therefore, Wilson disease is due to excess copper. \[ \boxed{\text{Copper}} \]