Question

Which of the following statements are true about Prions
A. Prion is a type of infectious protein 
B. Prions contain single stranded RNA 
C. Creutzfeldt‐Jakob disease (CJD) is not caused by Prion 
D. Prions are even more difficult to destroy than bacterial spores 
Choose the correct answer from the options given below:

• A. A, B and D only
• B. A only
• C. A and D only
• D. A, C and D only

Answer 1

The Correct Option is C

Let's analyze each statement to determine which are true regarding Prions:

1. A. Prion is a type of infectious protein
   True. Prions are unique infectious agents composed entirely of protein. They lack nucleic acids (DNA or RNA), which sets them apart from viruses, bacteria, and other pathogens.
2. B. Prions contain single-stranded RNA
   False. Prions do not contain either single-stranded or double-stranded RNA. They are composed solely of protein, specifically a misfolded form of the prion protein.
3. C. Creutzfeldt‐Jakob disease (CJD) is not caused by Prion
   False. Creutzfeldt‐Jakob disease (CJD) is, in fact, caused by prions. It is a neurodegenerative disorder associated with the accumulation of misfolded prion proteins in the brain.
4. D. Prions are even more difficult to destroy than bacterial spores
   True. Prions are notoriously difficult to destroy. They are resistant to conventional sterilization methods that inactivate other pathogens, including bacterial spores.

Given the analysis, the correct statements about Prions are A and D.

Conclusion: Therefore, the correct answer is: A and D only