Concept:
Generations of computers are classified based on the major technology used in their internal circuitry.
Step 1: First generation.
First generation computers used vacuum tubes.
\[
A \text{ is correct}
\]
Step 2: Second generation.
Second generation computers used transistors.
\[
B \text{ is correct}
\]
Step 3: Fourth generation.
Fourth generation computers used VLSI technology.
\[
C \text{ is correct}
\]
Step 4: Third generation.
Third generation computers used integrated circuits.
\[
D \text{ is correct}
\]
Step 5: Medium scale integration.
Medium scale integration is not the main technology of second generation computers. Second generation is mainly based on transistors.
\[
E \text{ is incorrect}
\]
Thus, the correct statements are:
\[
A,\ B,\ C \text{ and } D
\]
\[
\therefore \text{Correct Answer is (C)}
\]