Question

Which of the following statement is INCORRECT about enzyme substrate complex ?

• A. The substrate induces the enzyme to alter its shape.
• B. The substrate is completely bound to the enzyme.
• C. It breaks the chemical bonds of the substrate.
• D. The shape of an enzyme changes permanently after the formation of the enzyme-substrate complex.

Hint:

The enzyme regains its original shape after the products are released.

Answer 1

The Correct Option is D

Step 1: Understanding the Concept
The enzyme-substrate complex forms when the substrate binds at the active site of the enzyme.

Step 2: Check the statements
The substrate induces the enzyme to change its shape (induced fit): true.
The substrate is held firmly at the active site: true.
The strain helps to break the bonds of the substrate: true.

Step 3: Find the incorrect one
After the products leave, the enzyme regains its original shape and can be used again.
So the claim that its shape changes permanently is incorrect.

Final Answer:
The incorrect statement is that the enzyme's shape changes permanently. \[ \boxed{\text{(D) }\text{The shape of an enzyme changes permanently after the formation of the enzyme-substrate complex.}} \]