Question

Which enzyme converts trypsinogen into active trypsin in the digestive system?

• A. Pepsin
• B. Amylase
• C. Enterokinase
• D. Lipase

Hint:

Many digestive enzymes are produced in inactive forms (zymogens). Example: Trypsinogen → Trypsin (activated by enterokinase).

Answer 1

The Correct Option is C

Concept: In the digestive system, many enzymes are produced in an inactive form called a zymogen. This prevents the enzymes from digesting the tissues where they are produced. Trypsin is an important protein-digesting enzyme produced by the pancreas in an inactive form called trypsinogen.

Step 1: Location of activation. Trypsinogen is released into the small intestine where it becomes activated.

Step 2: Role of enterokinase. An enzyme called enterokinase (also known as enteropeptidase) is secreted by the intestinal lining. This enzyme converts trypsinogen into the active enzyme trypsin.

Step 3: Function of trypsin. Once activated, trypsin helps digest proteins into smaller peptides and also activates other pancreatic enzymes. Thus the enzyme responsible for activation is \[ \boxed{\text{Enterokinase}} \]