Question:
Which is a short acting non-depolarizing neuromuscular blocker?
Which is a short acting non-depolarizing neuromuscular blocker?
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It is hydrolysed by plasma cholinesterase, giving the briefest competitive block.
Updated On: Jun 24, 2026
- Rocuronium
- Suxamethonium
- Mivacurium
- Pancuronium
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The Correct Option is C
Solution and Explanation
Step 1: Non-depolarizing (competitive) neuromuscular blockers compete with acetylcholine at the nicotinic receptor of the motor end plate. They are graded by duration as short, intermediate or long acting.
Step 2: Mivacurium is the only short acting non-depolarizer in routine use. It is rapidly broken down by plasma pseudocholinesterase, giving a short clinical duration of roughly 15 to 20 minutes.
Step 3: Therefore mivacurium is the correct answer.
Step 4: The distractors: rocuronium is an intermediate acting non-depolarizer; pancuronium is a long acting non-depolarizer; and suxamethonium (succinylcholine) is short acting but is a depolarizing blocker, not a non-depolarizing one.
Step 2: Mivacurium is the only short acting non-depolarizer in routine use. It is rapidly broken down by plasma pseudocholinesterase, giving a short clinical duration of roughly 15 to 20 minutes.
Step 3: Therefore mivacurium is the correct answer.
Step 4: The distractors: rocuronium is an intermediate acting non-depolarizer; pancuronium is a long acting non-depolarizer; and suxamethonium (succinylcholine) is short acting but is a depolarizing blocker, not a non-depolarizing one.
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