Question:
Shortest acting non depolarizing muscle relaxant is?
Shortest acting non depolarizing muscle relaxant is?
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Which competitive blocker is metabolised by plasma pseudocholinesterase?
Updated On: Jun 24, 2026
- Mivacurium
- Doxacurium
- Pipecuronium
- Vecuronium
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The Correct Option is A
Solution and Explanation
Step 1: Non depolarizing (competitive) neuromuscular blockers act by competing with acetylcholine at the nicotinic receptor of the motor end plate. They are classified by duration of action.
Step 2: Mivacurium is the shortest acting non depolarizing muscle relaxant because it is rapidly hydrolysed by plasma pseudocholinesterase, giving it a brief duration of action.
Step 3: The distractors are longer acting. Doxacurium and pipecuronium are long acting agents, and vecuronium is an intermediate acting agent. Note that suxamethonium (succinylcholine) is the shortest acting skeletal muscle relaxant overall, but it is depolarizing, so among non depolarizing agents the answer is mivacurium.
Step 2: Mivacurium is the shortest acting non depolarizing muscle relaxant because it is rapidly hydrolysed by plasma pseudocholinesterase, giving it a brief duration of action.
Step 3: The distractors are longer acting. Doxacurium and pipecuronium are long acting agents, and vecuronium is an intermediate acting agent. Note that suxamethonium (succinylcholine) is the shortest acting skeletal muscle relaxant overall, but it is depolarizing, so among non depolarizing agents the answer is mivacurium.
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