Question:

Which hormone is used in estrus synchronization in cattle?

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Prostaglandin = CL regression = synchronized estrus!
  • Prolactin
  • Prostaglandin F2α
  • Insulin
  • Thyroxine
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The Correct Option is B

Approach Solution - 1

Estrus synchronization is used to bring a group of animals into heat simultaneously. This makes planned breeding and AI possible. Prostaglandin F2α is commonly used because it causes the regression of the corpus luteum (CL) in animals that are in diestrus phase. When the CL regresses, progesterone drops and the animal returns to estrus within 2–5 days. Other protocols may use progesterone devices (like CIDR) or GnRH for timed AI programs.
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Approach Solution -2

Mechanism-Based Approach: Estrus synchronization requires ending the current luteal phase quickly and predictably across many animals.

Prostaglandin F2α does exactly this — it causes luteolysis (breakdown of the corpus luteum), dropping progesterone and triggering a return to heat within days.

Prolactin, insulin, and thyroxine don't act on the corpus luteum at all, so none of them can synchronize a herd's cycle.
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