Question:
Interstitial cells of cajal called
Interstitial cells of cajal called
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Just as the SA node acts as the electrical pacemaker for the heart, the Interstitial Cells of Cajal (ICCs) serve as the electrical pacemakers for the digestive tract.
Updated On: Jul 8, 2026
- Slow pacemaker
- Pacemaker
- MMC
- MAPC
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The Correct Option is B
Solution and Explanation
Step 1: Understanding the Concept:
Gastrointestinal motility is governed by intrinsic electrical activity, which coordinates the cyclic contractions of the smooth muscle layers.
Step 3: Detailed Explanation:
The Interstitial Cells of Cajal (ICCs) are specialized cells located within the muscular layers of the gastrointestinal tract.
These cells function as the electrical pacemakers of the gut.
They spontaneously generate electrical slow waves (basic electrical rhythm), which spread to neighboring smooth muscle cells via gap junctions.
These slow waves set the baseline frequency of gastrointestinal contractions.
Let us briefly review the other options:
- MMC (Migrating Motor Complex): A distinct pattern of electromechanical activity observed in gastrointestinal smooth muscle during periods of fasting.
- MAPC (Multipotent Adult Progenitor Cells): A type of stem cell with the potential to differentiate into various cell types, unrelated to pacemaking.
Step 4: Final Answer
Interstitial cells of Cajal are designated as the pacemakers of the gastrointestinal tract.
Gastrointestinal motility is governed by intrinsic electrical activity, which coordinates the cyclic contractions of the smooth muscle layers.
Step 3: Detailed Explanation:
The Interstitial Cells of Cajal (ICCs) are specialized cells located within the muscular layers of the gastrointestinal tract.
These cells function as the electrical pacemakers of the gut.
They spontaneously generate electrical slow waves (basic electrical rhythm), which spread to neighboring smooth muscle cells via gap junctions.
These slow waves set the baseline frequency of gastrointestinal contractions.
Let us briefly review the other options:
- MMC (Migrating Motor Complex): A distinct pattern of electromechanical activity observed in gastrointestinal smooth muscle during periods of fasting.
- MAPC (Multipotent Adult Progenitor Cells): A type of stem cell with the potential to differentiate into various cell types, unrelated to pacemaking.
Step 4: Final Answer
Interstitial cells of Cajal are designated as the pacemakers of the gastrointestinal tract.
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