Question:
The targeting sequence of a polypeptide segment Lys-Asp-Glu-Leu in single letter code is __________.
The targeting sequence of a polypeptide segment Lys-Asp-Glu-Leu in single letter code is __________.
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Write out the single letter codes for Lysine, Aspartate, Glutamate and Leucine in order.
Updated On: Jul 4, 2026
- LAGE
- KAGL
- LDGE
- KDEL
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The Correct Option is D
Solution and Explanation
Step 1: Each amino acid has a standard single letter code, Lysine is K, Aspartate is D, Glutamate is E, and Leucine is L.
Step 2: Writing the sequence Lys-Asp-Glu-Leu in the same order using these letters gives K-D-E-L.
Step 3: This particular sequence, KDEL, is well known as the ER retention signal found at the C-terminus of proteins that must stay in the endoplasmic reticulum.
Step 4: So the correct single letter sequence is KDEL.
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