Question

The deficiency of vitamin ______ causes megaloblastic anemia.

• A. Vitamin B1
• B. Vitamin B2
• C. Vitamin B12
• D. Vitamin B6

Hint:

Megaloblastic Anemia = $B_{12}$ or Folic Acid deficiency.

Answer 1

The Correct Option is C

Step 1: Concept
Megaloblastic anemia is a condition where the bone marrow produces unusually large, structurally abnormal, immature red blood cells.

Step 2: Meaning
This condition arises from impaired DNA synthesis during erythrocyte production.

Step 3: Analysis
Vitamin B12 (Cyanocobalamin) and Folic acid are essential cofactors for DNA synthesis. A deficiency in either leads to megaloblastic changes.

Step 4: Conclusion
Therefore, Vitamin B12 deficiency is a primary cause of megaloblastic anemia.

Final Answer: (C)