Step 1: Concept
This is a problem of permutations with repetition.
Step 2: Meaning
A tripeptide has three positions to be filled. Since we can reuse amino acids, each position has the same number of choices.
Step 3: Analysis
For the first position, there are 3 choices. For the second, there are 3 choices. For the third, there are 3 choices. Total combinations = $3 \times 3 \times 3 = 3^3$.
Step 4: Conclusion
The total number of unique tripeptides possible is 27.
Final Answer: (D)