Question:
Sequentially arrange the following vascular changes in acute inflammatory response
(A) Vasoconstriction
(B) Blood flow becomes sluggish
(C) Vasodilatation
(D) Protein-rich fluid escapes from blood vessels
(E) WBCs adhere to the blood vessel wall
Choose the correct answer from the options given below:
Sequentially arrange the following vascular changes in acute inflammatory response
(A) Vasoconstriction
(B) Blood flow becomes sluggish
(C) Vasodilatation
(D) Protein-rich fluid escapes from blood vessels
(E) WBCs adhere to the blood vessel wall
Choose the correct answer from the options given below:
(A) Vasoconstriction
(B) Blood flow becomes sluggish
(C) Vasodilatation
(D) Protein-rich fluid escapes from blood vessels
(E) WBCs adhere to the blood vessel wall
Choose the correct answer from the options given below:
Show Hint
Remember that the very first vascular response is always a brief, protective vasoconstriction (A), followed immediately by persistent vasodilatation (C). This helps narrow down the sequence.
Updated On: Jul 23, 2026
- (A), (C), (D), (B), (E).
- (A), (B), (D), (E), (C).
- (C), (A), (E), (B), (D).
- (C), (B), (D), (A), (E).
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept:
Acute inflammation triggers a highly coordinated sequence of vascular and cellular events designed to deliver white blood cells (WBCs) and plasma proteins to the site of injury.
Detailed Explanation:
Let us review the standard chronological sequence of vascular events in acute inflammation:
1. (A) Transient Vasoconstriction: Immediately after injury, there is a momentary narrowing of local arterioles (lasting from seconds to a few minutes).
2. (C) Vasodilatation: Arteriolar dilation follows quickly, causing increased local blood flow (hyperemia) and heat/redness.
3. (D) Escape of protein-rich fluid: Increased microvascular permeability allows plasma proteins and fluid to leak out into the interstitial space (exudation), which leads to tissue swelling (edema).
4. (B) Sluggish blood flow (Stasis): The loss of fluid increases blood viscosity and concentration of red blood cells, causing the local circulation to slow down (blood flow becomes sluggish).
5. (E) WBC adhesion: Due to the stasis, leukocytes exit the central column of blood flow, marginate along the vessel wall, and adhere to activated endothelial cells (pavementing/adhesion) before migrating into the tissue.
Thus, the correct chronological sequence is:
\[ \text{(A) } \rightarrow \text{ (C) } \rightarrow \text{ (D) } \rightarrow \text{ (B) } \rightarrow \text{ (E)} \]
Step 2: Final Answer:
The correct sequence corresponds to Option (A).
Acute inflammation triggers a highly coordinated sequence of vascular and cellular events designed to deliver white blood cells (WBCs) and plasma proteins to the site of injury.
Detailed Explanation:
Let us review the standard chronological sequence of vascular events in acute inflammation:
1. (A) Transient Vasoconstriction: Immediately after injury, there is a momentary narrowing of local arterioles (lasting from seconds to a few minutes).
2. (C) Vasodilatation: Arteriolar dilation follows quickly, causing increased local blood flow (hyperemia) and heat/redness.
3. (D) Escape of protein-rich fluid: Increased microvascular permeability allows plasma proteins and fluid to leak out into the interstitial space (exudation), which leads to tissue swelling (edema).
4. (B) Sluggish blood flow (Stasis): The loss of fluid increases blood viscosity and concentration of red blood cells, causing the local circulation to slow down (blood flow becomes sluggish).
5. (E) WBC adhesion: Due to the stasis, leukocytes exit the central column of blood flow, marginate along the vessel wall, and adhere to activated endothelial cells (pavementing/adhesion) before migrating into the tissue.
Thus, the correct chronological sequence is:
\[ \text{(A) } \rightarrow \text{ (C) } \rightarrow \text{ (D) } \rightarrow \text{ (B) } \rightarrow \text{ (E)} \]
Step 2: Final Answer:
The correct sequence corresponds to Option (A).
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