Question:

Assertion (A) : Stratum lucidum is translucent layer present between stratum spinosum and stratum granulosum
Reasoning (R) : Stratum lucidum is translucent due to presence of eledin protein.
In light of the above statements, choose the correct answer from the options given below.

Show Hint

A useful mnemonic for remembering the layers of the epidermis from superficial to deep is: Come, Let's Get Sun Burned (Corneum, Lucidum, Granulosum, Spinosum, Basale).
This clearly shows that Stratum Lucidum lies between Corneum and Granulosum.
  • Both (A) and (R) are true and (R) is the correct explanation of (A).
  • Both (A) and (R) are true but (R) is NOT the correct explanation of (A).
  • (A) is true but (R) is false.
  • (A) is false but (R) is true.
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Concept:
The epidermis of thick skin (such as the footpads of dogs or palms/soles of humans) consists of five distinct histological layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.

Step 2: Detailed Explanation:

Let us analyze the Assertion (A):
The stratum lucidum is a thin, clear, translucent layer of dead skin cells in the epidermis.
It is situated between the stratum granulosum (below) and the stratum corneum (above).
The assertion states that it is located between the stratum spinosum and stratum granulosum, which is histologically incorrect because the stratum spinosum lies beneath the stratum granulosum.
Therefore, Assertion (A) is false.
Now let us analyze the Reasoning (R):
The translucency of the stratum lucidum is due to the presence of eleidin (or eledin), a clear intermediate protein product.
Eleidin is formed by the transformation of keratohyalin granules from the underlying stratum granulosum.
This protein does not stain well with standard histological dyes, giving the layer its characteristic clear or translucent appearance under light microscopy.
Therefore, Reasoning (R) is true.

Step 3: Final Answer:

Since Assertion (A) is false and Reasoning (R) is true, the correct option is (D).
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