Question:
Renin is released from:
Renin is released from:
Updated On: Jul 14, 2026
- Hepatocytes of liver
- Beta-cells of pancreas
- Microglial cells
- Juxtaglomerular cells (JGCs) of kidney
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The Correct Option is D
Approach Solution - 1
The correct option is (D): Juxtaglomerular cells (JGCs) of kidney.
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Approach Solution -2
The question asks which cells release renin. Let's check each of the listed cell types.
- Hepatocytes of liver: Liver cells produce angiotensinogen, the precursor protein that renin acts upon, but they do not themselves release renin.
- Beta-cells of pancreas: These cells produce and release insulin in response to rising blood glucose. They have no role in renin release.
- Microglial cells: These are the resident immune cells of the central nervous system, responsible for immune surveillance in the brain and spinal cord. They are unrelated to renin secretion.
- Juxtaglomerular cells (JGCs) of kidney: These specialized smooth muscle cells are located in the walls of the afferent arterioles of the kidney's glomeruli. They detect a drop in blood pressure or reduced sodium delivery and respond by releasing renin into the bloodstream, which starts the renin-angiotensin-aldosterone system.
Among the four cell types listed, only the juxtaglomerular cells of the kidney are the actual source of renin secretion.
Therefore, the correct answer is Juxtaglomerular cells (JGCs) of kidney.
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