Question

Match List I with List II

	List I-Drugs		List II-Classes
A	Anakinra	I	IL‐2 receptor antagonist
B	Basiliximab	II	TNFα inhibitors
C	Infliximab	III	Calcineurin inhibitors
D	Tacrolimus	IV	mTOR inhibitors
E	-	V	IL‐1 receptor antagonist

Choose the correct answer from the options given below:

• A. A ‐III , B ‐II , C ‐I , D ‐ IV
• B. A ‐V, B ‐II , C ‐III, D ‐ I
• C. A ‐I , B ‐III , C ‐V , D ‐II
• D. A ‐V , B ‐I , C ‐II , D ‐ III

Answer 1

The Correct Option is D

To solve this question, we need to match the drugs in List I with their respective classes in List II. Let's review each drug and determine its class.

1. Anakinra: Anakinra is known as an IL‐1 receptor antagonist. It is used to block the activity of interleukin-1, which plays a role in inflammation. Thus, it matches with Class V (IL‐1 receptor antagonist).
2. Basiliximab: Basiliximab is an IL‐2 receptor antagonist. It is primarily used as an immunosuppressant in organ transplantation to prevent rejection. Therefore, it belongs to Class I (IL‐2 receptor antagonist).
3. Infliximab: Infliximab is a TNFα inhibitor used in the treatment of autoimmune diseases such as rheumatoid arthritis. It matches with Class II (TNFα inhibitors).
4. Tacrolimus: Tacrolimus is a calcineurin inhibitor, which is also used as an immunosuppressant in organ transplantation to reduce organ rejection. Thus, it falls under Class III (Calcineurin inhibitors).

Based on the above analysis, the correct matching is: 

Drug	Class
Anakinra	V. IL‐1 receptor antagonist
Basiliximab	I. IL‐2 receptor antagonist
Infliximab	II. TNFα inhibitors
Tacrolimus	III. Calcineurin inhibitors

The correct option is:

A ‐V , B ‐I , C ‐II , D ‐ III