Read the following passage and answer the question that follow :
The data below shows the concentration of nicotine smoked by a smoker taking 10 puffs/minute.
[Graph: "Smoking Cigarette", concentration of nicotine in blood (mg/cm3) against time (minutes), 1 to 15. The line rises steadily from about 0 at 1 minute to a peak of 45 at 10 minutes, falls sharply to 20 at 11 minutes, then declines slowly to about 10 at 15 minutes.]
(b) How does cigarette smoking result in high blood pressure and increase in heart rate ?

What are the various routes by which transmission of human immunodeficiency virus takes place?
How does the transmission of each of the following diseases take place?
(a) Amoebiasis
(b) Malaria
(c) Ascariasis
(d) Pneumonia