Read the following passage and answer the question that follow :
The data below shows the concentration of nicotine smoked by a smoker taking 10 puffs/minute.
[Graph: "Smoking Cigarette", concentration of nicotine in blood (mg/cm3) against time (minutes), 1 to 15. The line rises steadily from about 0 at 1 minute to a peak of 45 at 10 minutes, falls sharply to 20 at 11 minutes, then declines slowly to about 10 at 15 minutes.]
(a) (i) With reference to the above graph, explain the concentration of nicotine in the blood at 10 minutes.

What are the various routes by which transmission of human immunodeficiency virus takes place?
How does the transmission of each of the following diseases take place?
(a) Amoebiasis
(b) Malaria
(c) Ascariasis
(d) Pneumonia